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Thank you for your feedback. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. The makers of Colgate Sensitive Pro-Relief and its rival, Sensodyne Rapid Relief, have been dobbing each other into the health regulator over advertising claims that the toothpastes give users "instant" relief to pain from sensitive teeth. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. Lg i kurv. J Dent. Free postage. Colgate Sensitive Pro-Relief Enamel Repair Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily 2016;36(3):4403. Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG. [8] that demonstrated the inherent ability of chemical interaction between arginine and type 1 collagen molecules in the salivary alkaline PH, thus resulting in endogenous calcium phosphate deposition on exposed dentinal tubules. A head-to-head comparative evaluation of these most effective bioactive agents, such as arginine and BAG-based desensitisers, was suggested by Martins et al. CONCLUSION: The study results support the following conclusions: (1) Colgate Sensitive Pro-Relief toothpaste provides a significantly more reduction in dentin hypersensitivity than Sensodyne. Colgate Sensitive Plus Toothpaste developed for sensitive teeth provides sensitivity protection And helps in Enamel Repair, Cavity . The authors declare that they have no competing interests (financial and non-financial) related to the article. 2020;20(3):101460. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. J Oral Sci. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. Colgate* Sensitive Pro-Relief TM/MC Toothpaste with Pro-Argin TM/MC Technology is the first toothpaste that is clinically proven to provide instant & lasting relief from dentin hypersensitivity. However, FCPS formulation showed 1% more improvement than Pro-argin and 7% more than strontium acetate-based dentifrices. 90 sold. Provides 24/7 sensitivity protection. Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. Plus it has the freshness you trust from Colgate! This binds to the negatively charged dentine surface like a magnet. With the exclusive Pro-Argin formula, it provides instant* and lasting** relief by plugging the channels to block tooth sensitivity. In addition, participants were asked to record the overall sensitivity of their day-to-day experience on provided VAS sheets reporting pain on brushing, taking hot or cold beverages, and rinsing with tap water for the six weeks of the study. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. 3. Pro-Argin Technology works through a natural process of dentin tubule occlusion that attracts arginine and calcium carbonate to the dentin surface to form a protective seal that provides instant relief.2 Tandkrmen remineraliserar tandemaljen fr att ge bttre motstnd mot syraattacker. Felix J, Ouanounou A. Dentin hypersensitivity: etiology, diagnosis, and management. Google Scholar. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. 75 ml. *with direct application and daily brushing. A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste. The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. in 2018 [17]. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6. The datasets analysed during the current study are available from the corresponding author on reasonable request. 2017;71:18. Written consent was obtained from all participants to participate in the six-week clinical trial. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. Was this answer helpful? Am J Dent. Hines D, Rinaudi L, Xu S, Lavender S, Pilch S: The Use of Confocal Laser Scanning Microscopy and a Novel Imaging Program for Quantifying Dentine Tubule Occlusion. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. Find products and services. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . Use regularly to enjoy long-lasting relief from sensitivity*. Lasting protection with regular use. Instant relief when applied directly to the sensitive tooth with the fingertip and gently massaged for 1 minute. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. J Clin Dent. It contains clinically proven Pro-Argin technology which provides instant and lasting sensitivity relief. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? Colgate Sensitive Pro-Relief Enamel Rebuild also: Fights cavities Strengthens enamel Freshens breath Vegan . 2017;30(4):2216. Colgate Sensitive Pro Relief Teeth Whitening Sensitivity Toothpaste, 75ml 4.9 out of 5 stars 12 7 offers from SAR 33.95 Colgate Sensitive Pro Relief Base Instant Sensitivity Relief Toothpaste, 75ml 4.3 out of 5 stars 20 5 offers from SAR 31.25 Colgate Total 12 hour Protection Pro - Gum Health Toothpaste 75ml Read our disclaimer for details. SA was the principal investigator and has contributed to design, data acquisition, analysis, and interpretation, and drafted the manuscript. Prevalence of dentin hypersensitivity: systematic review and meta-analysis. 75 ml. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. The effectiveness of Colgate SENSITIVE INSTANT Relief toothpaste is built on its Pro-Argin technology with arginine and calcium from calcium carbonate. A meta-analysis by Grnberg et al. Colgate Sensitive Pro-Relief Whitening Toothpaste provides clinically proven instant and lasting relief for sensitive teeth. Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. J Clin Dent. Tandkrmen innehller zink fr att strka tandkttet och frhindra att tandkttet drar sig tillbaka, vilket r en av de vanligaste orsakerna till att . Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke BMC Oral Health 21, 498 (2021). https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. 2019;40(10):6537 (quiz 8). [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). Oral Care Products | Colgate Professional, Colgate Toothpaste - Dentists & Patients | Colgate Professional, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste, Instantly* relieves dentine hypersensitivity, Long-lasting relief from the pain of sensitive teeth, Helps strengthen gums and prevent gum recession, Recommended fluoride level for caries protection (1450ppm). The clinical significance of this study can be highlighted by the fact that this was a person-centred clinical trial where patients were the prime focus where thepatients suffering from DH. The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. PubMed Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate Ingredients *Potassium Nitrate The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Aust Dent J. The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. WHAT IS Colgate SENSITIVE INSTANT Relief Repair & Prevent? Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. 2020;99(5):51422. The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. Tandkrmen har ett slipmedel som ger en mild polering och tar bort yttre flckar och fluor skyddar tnderna mot karies. We found more change in pain scores of VAS used for mechanical stimuli with Pro-argin than FCPS as shown in Table 5 that could be relatable with a randomised controlled trial of FCPS and arginine based desensitizers reporting better treatment response of arginine than FCPS in the cold stimulated DH after two weeks to one month, subsequently [40]. [9] stated in 2017 that arginine and strontium acetate-based desensitisers had equal clinical significance in reducing pain in DH and the other findings of the meta-analysis suggested that strontium acetate and Pro-argin should be compared for clinical efficacy immediately after topical application by independent health authorities. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). Am J Dent. 3 Report Deon Hines-0003, 2016. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. 2009;20(1):106. Trials. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Indian J Dent Sci. 2020;99(5):51422. 4Intervention D denotes Colgate Total. Gently removes stains and helps restore the natural whiteness of your teeth. Colgate Sensitive Pro-Relief toothpaste is a revolutionary and one-of-its kind remedy that can provide consumers suffering from Sensitivity the much needed instant and long lasting relief . Amsterdam: Elsevier; 2015. p. 4576. Mantzourani M, Sharma D. Dentine sensitivity: past, present and future. Pro-Argin technology provides instant* and long-lasting, Oral Care Products | Colgate Professional. The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. It has stannous fluoride as an active ingredient. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. Dentifrices were removed carefully after one minute of undisturbed application by rinsing the air lightly with an air syringe, and the subject was asked to spit. Colgate Sensitive PRO-Relief provides you relief from sudden shocks of pain and long-term sensitivity with regular use. No adverse events like gingival inflammation, bad taste, allergies, fluoride incompatibility, and dental or tongue stains were observed for all dentifrices. Colgate Total with stannous fluoride also offers more benefits than ever before, including sensitivity relief, improved enamel strength* and odor neutralization* (*based on in vitro studies).Colgate Total Advanced Whitening is a tooth whitening toothpaste that provides stain removal and prevention. Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. Correspondence to Helps protect teeth against cavities and promotes healthy gums (with regular brushing). J Clin Dent. Cookies policy. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. Delivering better oral health - An Evidence-based toolkit for prevention. We observed the varying treatment response at different efficacy intervals that could be due to the varying degree of patient's response to pain-provoking stimuli in DH. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste delivers instant* and long-lasting sensitivity relief plus gum protection. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. J Dent. Holland G, Narhi M, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Then, the repeated measure was obtained after five minutes for previous pain recovery, and dentifrices were provided to the patient for self-application. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. They reported more clinical efficacy with BioMin than Pro-argin reduction in air-blast stimulated DH on VAS after one month [39]. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. Patel VR, Shettar L, Thakur S, Gillam D, Kamala DN. The New Colgate Sensitive Instant* Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. There is no problem with every day and prolonged use. * *With continued use twice a day Prevents sensitivity from coming back* *With continued use twice a day can help prevent sensitivity from coming back. Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. Treatments provided to the patients were OTC dentifrices marketed with the claim of immediate pain relief in DH. Grading of Recommendations, Assessment, Development and Evaluations. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. Compend Contin Educ Dent. These dentifrices were extracted in a plain tube by the dental assistant from commercial packing and labelled with treatment codes to keep the principal investigator and participants blinded at the time of treatment assignment. YES Somewhat No It was found statistically significant relative to control on all clinical parameters of the SCASS and VAS. By using this website, you agree to our All rights reserved. Results of our study, together with the results of the previous studies, confirm the immediate clinical efficacy of Pro-argin for the relief of DH. In vitro analysis suggested that FCPS-based dentifrice enabled the slow and sustained release of fluoride contents, resulting in more stable fluorapatite crystals in saliva [14, 15]. See patient relevant information on Colgate.com. 2009;20 (Spec Iss):123130. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. PubMedGoogle Scholar. 1. 2009;22:3A-7A. These commercially available tooth paste are one n the same thing.Both says they work in reducing the tooth senstivity due to cold intake.These may help olny during the early stages but when there is sensation to both cold and hot drinks and pain, you need to visit a dentist. Plain bi-carb soda and coconut butter do a far better job at cleaning and desensitising. It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. All authors read and approved the final manuscript. Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. Gillam D, Hill R, Samueli A. Bioactive glasses in the management of dentine hypersensitivity: a review. Blocks the pain of sensitive teeth. IADR, The Excel, United Kingdom. Pro-Argin technology is occlusive. For more great Dental Care products like toothpaste and mouthwash, continue browsing online and buy in-store at B&M. Colgate Sensitive Instant Relief Toothpaste 75ml Product code: 326795 2.49 Subject to availability - visit your nearest store The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. The next study outcome of our study wasrelated to 8% strontium acetate with clinical reduction of 37.6% on SCASS and 46% on VAS from baseline using mechanical and water jet stimuli immediately after topical application on sensitive teeth as depicted in Tables 3, 5, and 6. The secondary analysis population could be described as 20 participants per treatment group out of 35 enrolled in the six-week trial who responded to mechanical and water jet stimuli on VAS with scores of4 as secondary outcome measures. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Get the freedom to forget about tooth sensitivity with Colgate Sensitive Pro-Relief Complete Protection Toothpaste. WHAT IS THE FLUORIDE CONTENT OF Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE? reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity. Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. Dent Health Curr Res. Martins CC, Firmino RT, Riva JJ, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. A previously published study by Samueli et al. 2013;41(2):18794. Madurai: Best Dental Science College; 2020. [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26].
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